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For new NGS companies, rising with the tide will become all the more challenging as veteran companies continue to innovate. Which new technologies will stay afloat in a flooded NGS market? That remains to be seen. Indeed, James Hadfield, PhD, a genomics expert and the senior director of epigenomics, Oncology Translational Medicine, AstraZeneca, tweeted, “2022 could be as important as 2006.” Several new NGS platforms, including those developed by Singular Genomics, Element Biosciences, and Ultima Genomics, made entrances that could put pressure on Illumina. The other hose? New next-generation sequencing (NGS) technologies. Kevin King, MD, PhD, assistant professor of medicine/cardiology and bioengineering at the University of California, San Diego, discussed how spatial technology is being used to survey infarct and border zones in ischemic heart disease. William Hwang, MD, PhD, an assistant professor of radiation oncology at the Massachusetts General Hospital Cancer Center, described how spatial technology is being used to capture interactions among different cell types in treatment-resistant pancreatic cancer. The focus on spatial was evident from the beginning of the conference, when two early talks included spatial data. Attendees could not escape the multicolored images of labeled tissues-from figures neatly positioned on posters to marketing images splayed across entire walls of the conference center. Speakers shared their excitement over new discoveries, and exhibitors included established companies that were intent on consolidating their positions, as well as newcomers determined to carve out their own niches. The first let loose a steady stream of information about progress in spatial biology.
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